Multifunctional pellet making, granulating and coating machine


Equipment Description: The multifunctional granulator and coating machine adopts a modular design. Different functional modules can be added according to usage requirements, realizing the free switching of centrifugal granulation, extrusion rolling, and cutting spray granulation. Through the quick conversion of the rotating disc and the gear disc, the machine simultaneously has the functions of starting, granulating, coating, extruding, and rolling. It has two microsphere preparation methods: centrifugal granulation and tangential spray granulation. Finished microspheres can also be put into the material tank and sprayed with atomized coating liquid for coating. The microspheres have good sphericity, uniform size, and high drug utilization rate. They are suitable for sustained-release drug granulation, enteric-coated drug granulation, microsphere coating, and other processes. It is an ideal equipment for exploring microsphere preparation processes and formula development. The application of microspheres in the field of pharmaceutics is very extensive. As a drug carrier, it can be further pressed into tablets or put into empty capsules. This not only improves drug stability, but also effectively regulates the drug release rate; as a drug delivery system, microspheres have therapeutic advantages, such as less gastrointestinal irritation and reduced risk of drug bolus release, improving drug safety and good reproducibility of blood drug concentration; microspheres also have good fluidity, low friability, easy filling, and other processing advantages.
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