Product Series
Product Introduction: The extrusion rolling machine is mainly suitable for microsphere preparation technology. Its working principle is to use a rotating screw to convey and extrude wet raw materials to a spherical dome. The spherical dome extrudes the materials into strips, and then uses a high-speed rotating gear disc to roll the strip-shaped materials into dense spherical microspheres. Microspheres have been widely used in the field of pharmaceutics. As a drug carrier, it can be further pressed into tablets or filled into empty capsules. It not only improves drug stability but also effectively regulates the drug release rate; as a drug delivery system, microspheres have therapeutic advantages, such as less gastrointestinal irritation and reduced risk of drug burst release, improving drug safety and good blood drug concentration reproducibility; microspheres also have good fluidity, low friability, easy filling and other process advantages. In pharmaceutical production, compared with other methods of making pills, extrusion rolling technology is an advanced process method widely used in the international pharmaceutical industry. In controlled-release preparations and drug utilization, many factors in extrusion rolling can change the powder properties of microspheres and the release behavior of drugs; the measurement indicators of microsphere quality mainly include: microsphere particle size, roundness, friability, density, fluidity, drug dissolution and the microstructure of the microsphere surface, etc. Through independent and detailed examination of various factors, the properties of microspheres can be improved purposefully to achieve the expected drug purpose.
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No. 2, No. 712 Xiangfu Avenue, Shuangfu Street, jiangjin district, Chongqing
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