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From which aspects should solid preparation equipment enterprises conduct in-depth research? Article link: China Pharmaceutical Network http://www.zyzhan.com/news/Detail/59011.html
Solid preparations have advantages such as high physical and chemical stability, low production cost, and convenient administration and portability. They are the most widely used and numerous dosage forms in pharmaceuticals and occupy a significant share in drug preparations. To promote the development of solid preparations, China's solid preparation equipment industry has made rapid progress in recent years, with a number of excellent solid preparation equipment manufacturing enterprises possessing independently developed technologies and continuous innovation capabilities.
Although China's solid preparation equipment industry has made rapid progress over the years, granulation remains the core process in solid preparation production. However, there are very few suppliers who can provide pharmaceutical companies with complete sets of equipment and solutions for solid preparation granulation (including three granulation processes: wet granulation, fluidized bed granulation, and dry granulation).
The author learned that Canaan Technology is one of the few domestic companies with the corresponding technical capabilities. It can provide customers with complete sets of equipment and solutions for solid preparation granulation. It is currently one of the few domestic suppliers that can provide complete sets of equipment and solutions for three granulation processes (wet granulation, fluidized bed granulation, and dry granulation). Products include wet granulation series, fluidized bed drying/granulation series, dry granulation series, elevating series, mixing series, coating series, cleaning series, and pharmaceutical containers, covering 96 models and more than 600 specifications.
In addition, the GFL solid preparation production line unit produced by Zhiyang Machinery adopts traditional granulation technology, scientifically and effectively combining wet granulation, fluidized bed drying granulation, and wet regranulation units according to process characteristics to form a complete solid preparation production line. While retaining the independent use functions of each unit, the unit is equipped with a pipeline hot air curing device for hoppers with high viscosity. This greatly improves the production efficiency and automation level of the equipment, significantly reducing labor intensity.
With continuously improving technology content and shortening manufacturing cycles, solid preparation production line equipment will continue to develop towards informationization, digitalization, refinement, high speed, and automation, significantly enhancing the industry's general strength and core competitiveness. In addition, the development of solid preparation production line equipment should also focus on energy saving and comprehensive energy utilization, and the development of automatic control technology for production line equipment to ensure the achievement of optimal operating conditions.
With the increasing market attention to environmental protection, improving the equipment's environmental protection measures to reduce dust and exhaust emissions will also be a direction for solid preparation production line equipment to explore further.
The safety hazards, quality risks, and increased costs caused by dust generated during the production of solid preparations are thorny issues faced by all manufacturers and are also a focus of the new GMP. So how should enterprises solve these problems and make GMP certification smoother? According to the relevant person in charge of Beijing Changfeng Jinding Technology, a dust-free operation system for solid preparations can be achieved through dust-free pulverization systems, dust-free charging systems, vacuum conveying systems, closed automatic batching systems, and closed...
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